Peer-reviewed veterinary case report
High heart troponin levels in dogs after generalised seizures
By Dutton, E et al.·Published in The Journal of small animal practice·2018·Cheshire Cardiology, United Kingdom·View original on PubMed →
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Original publication title: Serum cardiac troponin I concentrations in dogs with generalised seizures.
- Species:
- dog
Plain-English summary
A group of dogs that recently had generalized seizures were found to have higher levels of a heart protein called cardiac troponin I compared to healthy dogs. This suggests that the seizures might be linked to some heart damage. The study noted that older dogs and those that had more seizures had even higher levels of this protein. If your dog has had seizures, it might be worth discussing these findings with your veterinarian to ensure their heart health is monitored.
People also search for: dog seizures heart problems · elevated troponin I in dogs · why is my dog having seizures
Abstract
OBJECTIVES: To determine if serum cardiac troponin I concentrations - measured with both a first-generation assay and a high-sensitivity assay - were greater in dogs with generalised seizures than in controls and to identify clinical variables associated with cardiac troponin I concentration. MATERIALS AND METHODS: Prospective study of 30 dogs with recent generalised seizures and 30 healthy controls. Serum cardiac troponin I concentration was measured using two commercially available assays, and the correlation of clinical factors with concentration was examined. RESULTS: Serum concentrations of cardiac troponin I were higher in dogs that had recent seizures compared to controls when measured by both assays. The predictors most clearly associated with cardiac troponin I concentration were number of seizures and age. Both predictors were positively associated with increasing concentrations of troponin I. CLINICAL SIGNIFICANCE: Serum cardiac troponin I concentration was significantly elevated in dogs that had recent generalised seizures when compared to controls, and concentrations were higher in dogs that experienced more seizures. This association may indicate that generalised seizures are associated with damage to the myocardium.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/29023739/