Peer-reviewed veterinary case report
Serum fructosamine test helps diagnose kidney sugar loss in dogs
By Thoresen, S I & Bredal, W P·Published in Research in veterinary science·1999·Department of Small Animal Clinical Sciences·View original on PubMed →
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Original publication title: Serum fructosamine measurement: a new diagnostic approach to renal glucosuria in dogs.
- Species:
- dog
Plain-English summary
Four dogs with high sugar levels in their urine (glucosuria) were tested for diabetes, but their blood sugar levels were normal. Instead, the vets used a test called serum fructosamine to check their long-term blood sugar levels. This test showed that the dogs did not have diabetes, helping to identify other conditions like primary renal glucosuria or Fanconi syndrome. The serum fructosamine test proved to be a simple and effective way to rule out diabetes in these cases, allowing for better diagnosis and treatment options.
People also search for: dog glucosuria causes · dog kidney disease symptoms · how to test for diabetes in dogs
Abstract
Measurement of serum fructosamine, 1-amino-1-deoxyfructose, is commonly used in diagnosing and monitoring hyperglycaemic disorders, such as diabetes mellitus in dogs. Serum fructosamine indicates long-term serum glucose concentrations and replaces serial serum glucose measurements. This study investigates the clinical usefulness of serum fructosamine in differentiating conditions other than diabetes mellitus characterised by glucosuria. Four dogs presented with glucosuria all had serum fructosamine concentrations within or close to the reference range (313 micromol 1(-1), 291 micromol 1(-1), 348 micromol 1(-1), 262 micromol 1(-1) reference range: 250 to 320 micromol 1(-1) indicating that a single serum fructosamine measurement is a simple and efficient way of verifying concurrent persistent normoglycaemia. Therefore, serum fructosamine is a useful parameter not only in diabetic patients, bu also in differentiating conditions in dogs characterised by glucosuria without hyperglycaemia, such as primary renal glucosuria and the Fanconi syndrome. To distinguish between primary renal glucosuria and the Fanconi syndrome, measurement of the amino acid concentration in urine was performed.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/10607507/