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Peer-reviewed veterinary case report

Severe tularemia in a patient on arthritis treatment - what to know

By Calin, Ruxandra et al.·Published in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases·2017·Infectious and Tropical Diseases Department, France·View original on PubMed

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Original publication title: Severe glandular tularemia in a patient treated with anti-tumour necrosis factor for psoriatic arthritis.

Movement & joints

Plain-English summary

This report describes a case of a person who developed a serious infection called glandular tularemia while being treated with a medication for psoriatic arthritis. The patient needed a long course of antibiotics, specifically doxycycline and ciprofloxacin, because their symptoms returned shortly after stopping ciprofloxacin. The findings suggest that tularemia might be more severe in people taking anti-TNF medications, which could mean they need stronger treatment.

Abstract

A case of severe glandular tularemia in a patient receiving anti-tumour necrosis factor (TNF) therapy is reported here. The patient required prolonged treatment with doxycycline-ciprofloxacin due to early relapse after ciprofloxacin was stopped. Tularemia may have a more severe course in patients receiving anti-TNF. This may thus be an indication for more aggressive treatment.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/28450199/