Peer-reviewed veterinary case report
Dog with severe iron overload and immune-mediated anemia
By K. Zersen et al.·Published in Veterinary clinical pathology·2022·View original on Semantic Scholar →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Severe hyperferremia and hyperferritinemia in a dog with precursor‐directed immune‐mediated anemia
- Species:
- dog
Plain-English summary
A 4-year-old dog was brought to the vet because she was very tired and not eating for a day. Blood tests showed she had severe anemia, with extremely high levels of iron and ferritin in her blood. After further testing, the vet diagnosed her with a type of immune-mediated anemia, where the body attacks its own red blood cells. Fortunately, after starting treatment, her iron levels improved significantly, indicating that the treatment was effective.
People also search for: dog lethargy not eating · immune-mediated anemia treatment in dogs · high iron levels in dogs
Abstract
Abstract A 4‐year‐old dog was evaluated at the Colorado State University Veterinary Teaching Hospital for lethargy and hyporexia of 24 hours duration. On presentation, she had a marked normocytic, normochromic, nonregenerative anemia (HCT 14%; RI 40–55). Her serum iron concentration (1651 μg/dL; RI 73–245) and serum ferritin concentration (1337 ng/mL; RI 89–489) were markedly elevated. Bone marrow aspirate and core biopsy were consistent with a diagnosis of precursor‐directed immune‐mediate anemia. To the authors' knowledge, these are the highest reported serum iron and ferritin concentrations in a patient with precursor‐directed immune‐mediate anemia. The iron concentration improved significantly after treatment, supporting the theory that the hyperferremia was due to hemolysis and ineffective erythropoiesis.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on Semantic Scholar: https://www.semanticscholar.org/paper/35578377