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Peer-reviewed veterinary case report

Severe hypophosphatemia associated with diabetes mellitus in six dogs and one cat.

Journal:
Journal of the American Veterinary Medical Association
Year:
1987
Authors:
Willard, M D et al.

Plain-English summary

In a study involving six diabetic dogs and one diabetic cat, all of them were found to have very low levels of phosphorus in their blood, a condition known as severe hypophosphatemia. The cat experienced a breakdown of red blood cells, and one of the dogs had seizures, both likely due to the low phosphorus levels. Interestingly, five other pets had similar low phosphorus levels but did not show any signs of illness. This suggests that the symptoms can vary widely among pets, even with similar blood test results. Overall, the findings highlight the complexity of managing diabetes and its potential effects on phosphorus levels in pets.

Abstract

Severe hypophosphatemia was found in 6 diabetic dogs and in one diabetic cat. The cat suffered from hemolysis, and one dog had seizures, both apparently as a result of the severe hypophosphatemia. Clinical signs were not determined solely by the serum concentration of phosphorus, as seen in 5 other patients that did not have signs of disease despite similar serum phosphorus concentrations.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/3570950/