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Peer-reviewed veterinary case report

Dog with dry mouth diagnosed with Sjögren's-like syndrome

By Nabeta, Rina et al.·Published in The Journal of veterinary medical science·2019·Tokyo University of Agriculture and Technology, Japan·View original on PubMed

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Original publication title: Sjögren's-like syndrome in a dog.

Species:
dog

Plain-English summary

A neutered male Golden Retriever was brought in with a two-week history of a dry mouth. Tests showed that his salivary glands were swollen and had abnormal areas, which led to a diagnosis of Sjögren's-like syndrome, a condition similar to one seen in humans. The vet started treatment with immunosuppressive drugs, which quickly improved the dog's symptoms and the abnormal findings on ultrasound. This case highlights how ultrasound can be useful in tracking treatment progress in pets with this condition.

People also search for: dog dry mouth treatment · Golden Retriever salivary gland swelling · Sjögren's syndrome in dogs

Abstract

A neutered male Golden Retriever was referred with a 2-week history of dry mouth. Multiple and bilateral enlargement of the lacrimal and salivary glands showing heterogeneous internal enhancement was identified on contrast-enhanced computed tomography (CT). Ultrasonographic examination detected multifocal hypoechoic areas within the swollen submandibular salivary glands, which were histopathologically diagnosed as lymphoplasmacytic sialoadenitis. As both imaging and histopathological findings were in accordance with those in human Sjögren's syndrome, a provisional diagnosis of Sjögren's-like syndrome was made. Immunosuppressive drugs promptly improved clinical signs concurrently with the abnormal sonographic findings, indicating the feasibility of ultrasonography in monitoring therapeutic outcomes. Herein, we discuss a proposed criteria set for diagnosis of Sjögren's-like syndrome in veterinary medicine.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/31092740/