Peer-reviewed veterinary case report
Dog with T-cell lymphoma spreading to skeletal muscles
By Magni, Tommaso et al.·Published in Veterinary medicine and science·2023·Veterinary Clinic Pet Care, Italy·View original on PubMed →
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Original publication title: Skeletal muscle dissemination in a dog with T-cell lymphoma.
- Species:
- dog
Plain-English summary
A 5-year-old spayed female American Staffordshire was brought in because she was weak, reluctant to move, and had a swollen belly. She had recently had surgery to remove a mass thought to be a type of skin cancer called non-epitheliotropic cutaneous T-cell lymphoma. After imaging tests, the vet found that the cancer had spread to her abdominal muscles and created nodules in her skeletal muscles. Unfortunately, this case highlights that muscle metastasis from lymphoma can occur in dogs, which is rare but important for pet owners to be aware of.
People also search for: dog weakness swollen belly · American Staffordshire lymphoma treatment · dog muscle cancer symptoms
Abstract
A 5-year-old spayed female American Staffordshire was referred for weakness, reluctance to move and distension of the abdomen. Three weeks before, the dog underwent surgery for excision of a nodular mass suspected to be a non-epitheliotropic cutaneous T-cell lymphoma (NE-CTCL). Computed tomography revealed heterogeneous enhancing mesenteric masses and nodular lesions of soft tissue density, and infiltration of the abdominal muscular wall. Moreover, a pattern of diffuse muscle nodules in the skeletal muscles was visible, with lesions showing homogenous, heterogeneous or ring enhancement. Necrosis was histologically observed and these lesions were infiltrated by CD3-positive and CD20-, CD79a- and Iba1-negative neoplastic lymphocytes. On the basis of the immunopathological features metastatic NE-CTCL was suspected. Skeletal muscle metastasis has been rarely reported in small animals and this case report further confirms that this possibility should be considered in dogs with lymphoma.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/36571805/