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Peer-reviewed veterinary case report

Cat with fragile skin and multicentric follicular lymphoma

By Crosaz, Odile et al.·Published in Journal of feline medicine and surgery·2013·Paris-Est University, France·View original on PubMed

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Original publication title: Skin fragility syndrome in a cat with multicentric follicular lymphoma.

Species:
cat
LymphomaSkin & coatCats

Plain-English summary

An 11-year-old spayed female domestic shorthair cat was brought in for a wound on her right side. During the exam, the vet found a skin tear and noticed that her skin was fragile, with unusual star-shaped lesions appearing on their own. Further tests revealed that she had multicentric lymphoma, a type of cancer, which likely contributed to her skin issues. Unfortunately, her condition worsened, and she passed away. This case highlights the connection between skin fragility syndrome and lymphoma in cats, suggesting that lymphoma should be considered when a cat shows signs of fragile skin.

People also search for: cat skin problems · cat lymphoma symptoms · why is my cat's skin fragile · feline skin fragility syndrome · cat cancer treatment options

Abstract

An 11-year-old, spayed female domestic shorthair cat was presented for a right flank wound. On clinical examination, a single non-painful skin tear lesion with irregular edges was detected. During the examination, star-shaped cigarette paper-like skin lesions appeared spontaneously. An abdominal mass was also palpated. Feline skin fragility syndrome (FSFS) was suspected and a multicentric lymphoma was diagnosed by fine needle aspiration. The cat's condition declined and it died spontaneously. Post-mortem examination confirmed the diagnosis of lymphoma. Neoplastic lymphocytes were not observed in the skin. Histological analysis of the skin was consistent with the morphological aspects of FSFS. A possible direct link between the two conditions remains a matter of speculation, but this case report provides the first description of FSFS associated with multicentric follicular lymphoma. Thus, multicentric follicular lymphoma should be considered as a differential diagnosis in cats presenting with FSFS.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23580701/