Peer-reviewed veterinary case report
Small molecule inhibitors in veterinary oncology practice.
- Journal:
- The Veterinary clinics of North America. Small animal practice
- Year:
- 2014
- Authors:
- London, Cheryl A
- Affiliation:
- The Ohio State University · United States
Abstract
Recent advances in molecular biology have permitted the identification and characterization of specific abnormalities regarding cell signaling and function in cancer cells. Proteins that are found to be dysregulated in cancer cells can serve as relevant targets for therapeutic intervention. Although there are several approaches to block proteins that contribute to cellular dysfunction, the one most commonly used involves a class of therapeutics called small molecule inhibitors. Such inhibitors work by disrupting critical pathways/processes in cancer cells, thereby preventing their ability to grow and survive.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/25174906/