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Peer-reviewed veterinary case report

Sodium monofluoroacetate poisoning signs and treatment in dogs

By Goh, C S S et al.·Published in Australian veterinary journal·2005·University Veterinary Centre, United Kingdom·View original on PubMed

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Original publication title: Sodium monofluoroacetate (Compound 1080) poisoning in dogs.

Species:
dog

Plain-English summary

A dog can suffer from serious poisoning if it accidentally ingests sodium monofluoroacetate, commonly known as Compound 1080, which is used as a pesticide. Symptoms of poisoning can include vomiting, tremors, and seizures, and early recognition is crucial for a better chance of recovery. While there is no specific antidote for this type of poisoning, treatments such as activated charcoal, calcium salts, and peritoneal dialysis may help. Following a treatment protocol can improve the dog's chances, but prevention through safety measures is essential to avoid future incidents.

People also search for: dog poisoning symptoms · Compound 1080 treatment for dogs · how to treat dog pesticide poisoning

Abstract

Sodium monofluoroacetate (Compound 1080) is a widely used pesticide for control of feral animals such as the fox. Accidental poisoning of domestic animals occurs despite strict regulations on 1080 usage. Dogs are particularly susceptible to the toxin. The mechanism of 1080 toxicity, susceptibility of target and non-target species, persistence of 1080 in the environment and risk of accidental poisoning are discussed. Particular emphasis is placed on 1080 toxicity in the dog. Early recognition of intoxication is most important for prognosis and relies upon characteristic clinical signs and diagnostic findings. The treatment of 1080 intoxication remains a challenge with no proven antidotes. However, there are possible benefits from monoacetin, acetamide, calcium salts, colestipol, activated charcoal, peritoneal dialysis, sodium bicarbonate, neurotransmitter modulators and four-methylpyrazole. A recommended treatment protocol for 1080 toxicosis in dogs is included. Safety measures such as the use of wire dog muzzles and investigating alternatives to 1080 in pest control programs may be the key to reducing the incidence of future accidental poisonings.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16119418/