Peer-reviewed veterinary case report
Aggressive bone tumor in a 10-year-old longhair cat's jaw
By Malkawi, Mays A et al.·Published in Open veterinary journal·2025·Department of Clinical Veterinary Sciences·View original on PubMed →
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Original publication title: Solid type primary intraosseous squamous cell carcinoma in a long hair cat.
- Species:
- cat
Plain-English summary
A 10-year-old spayed female domestic longhair cat was brought to the vet with a growing mass on her jaw that caused her pain, excessive drooling, and a loss of appetite over six weeks. After various tests, including blood work and imaging, the diagnosis was confirmed as a rare and aggressive bone cancer called primary intraosseous squamous cell carcinoma. Unfortunately, due to the severity of the condition and poor prognosis, the decision was made to euthanize her to prevent further suffering.
People also search for: cat jaw tumor · why is my cat drooling · cat cancer symptoms · cat inappetence treatment · euthanasia for cats with cancer
Abstract
BACKGROUND: Primary intraosseous squamous cell carcinoma (PIOSCC) is a rare and aggressive malignancy that originates within the bone, reported in both humans and animals. While squamous cell carcinoma is the most common oral tumor in cats, PIOSCC is an uncommon variant with distinct clinical and pathological features. CASE DESCRIPTION: A 10-year-old spayed female domestic longhair cat presented with a progressively enlarging mass at the rostral mandible. Over 6 weeks, the cat exhibited clinical signs including inappetence, excessive salivation, and pain. Diagnostic evaluations comprised hematology, serum biochemistry, head radiographs, fine needle aspiration, and histopathology. A diagnosis of solid-type PIOSCC was confirmed post-mortem, based on histopathological and immunohistochemical findings. CONCLUSION: This case represents the first documented instance of solid-type PIOSCC in a cat in Jordan. It highlights the importance of early recognition and accurate diagnosis of this rare, locally invasive tumor. Given the poor prognosis, humane euthanasia was chosen as the most appropriate course of action.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/41630734/