Peer-reviewed veterinary case report
Gastroduodenal perforations in dogs linked to NSAID use and surgery
By Cariou, M et al.·Published in The Veterinary record·2009·Department of Veterinary Clinical Sciences, United Kingdom·View original on PubMed →
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Original publication title: Spontaneous gastroduodenal perforations in dogs: a retrospective study of 15 cases.
- Species:
- dog
Plain-English summary
Fifteen dogs with serious stomach issues were treated for spontaneous perforations (holes) in their stomach or upper intestine. Symptoms varied, but many showed signs of severe abdominal pain and distress. The dogs underwent surgery, and while some did not survive, most of the dogs that did make it through surgery had a good recovery. The study found that dogs who had previously taken non-steroidal anti-inflammatory drugs (NSAIDs) were more likely to develop these perforations.
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Abstract
The clinical findings and outcomes following surgical management of spontaneous gastroduodenal perforations in 15 dogs were reviewed in a retrospective study to identify related risk factors. Clinical and clinicopathological findings were diverse. Use of multiple diagnostic procedures yielded a strong index of suspicion for gastrointestinal perforation. There was a trend towards improved survival for animals with perforation of the gastric fundus/body compared to pyloric or duodenal perforation, although the difference was not statistically significant. Five dogs were euthanased at surgery; two dogs died within two days after surgery. Seven of the eight surviving dogs had a favourable long-term outcome. Previous administration of NSAIDs was the only identified predisposing factor in ten of 10 of the dogs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19820258/