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Peer-reviewed veterinary case report

Spontaneous shrinking of bone cancer in four dogs

By Mehl, M L et al.·Published in Journal of the American Veterinary Medical Association·2001·Department of Clinical Sciences, United States·View original on PubMed

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Original publication title: Spontaneous regression of osteosarcoma in four dogs.

Species:
dog
OsteosarcomaMovement & jointsDogs

Plain-English summary

Four dogs were diagnosed with a type of bone cancer called osteosarcoma, which is more common in dogs than in humans. Surprisingly, these dogs showed signs of improvement without any specific treatment, as the tumors began to shrink on their own. This spontaneous regression of the cancer is very rare in both dogs and humans. While the exact reasons for this phenomenon are still unclear, it offers hope for future cases of osteosarcoma in pets.

People also search for: dog osteosarcoma treatment · why is my dog limping · signs of bone cancer in dogs

Abstract

Spontaneous regression of primary malignant bone tumors is rare but has been reported in the human literature. To the authors' knowledge, spontaneous regression of primary bone tumors in dogs or cats has not been reported. Osteosarcoma (OSA) is the most common primary bone tumor in humans, and it has been reported that the incidence of OSA is 40 to 50 times greater in dogs than humans. In this report, high-grade OSA was diagnosed in biopsy specimens obtained from 4 dogs that subsequently underwent spontaneous regression without tumor-specific treatment. Osteosarcoma in dogs has characteristics similar to that of OSA in humans.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/11549088/