Peer-reviewed veterinary case report
Squamous cell anal sac cancer in two cats and treatment outcomes
By Kopke, M A et al.·Published in The Journal of small animal practice·2021·School of Veterinary Science·View original on PubMed →
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Original publication title: Squamous cell carcinoma of the anal sac in two cats.
- Species:
- cat
Plain-English summary
A 10-year-old male domestic shorthair cat was diagnosed with squamous cell carcinoma (a type of skin cancer) in the anal sac after showing signs of discomfort. The cat underwent surgery, radiation, and a medication called toceranib phosphate, but the cancer returned after about 236 days. Unfortunately, despite additional treatment with carboplatin, the cancer progressed, and the cat was euthanized 552 days after the initial surgery. Another cat with a similar diagnosis was treated with pain relief and supportive care but was euthanized 28 days later due to declining health.
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Abstract
This report describes two cases of feline anal sac squamous cell carcinoma. Cat 1 was managed with a multimodal approach combining surgical resection, radiation therapy and systemic therapy (toceranib phosphate; Palladia™) until local recurrence was identified at 236 days postsurgery. At that time, the cat received carboplatin. With the tumour being progressive, the cat was euthanased 552 days post initial surgery. Cat 2 was managed palliatively with a non-steroidal anti-inflammatory (meloxicam) and supportive medications. Unfortunately, with further decline in quality of life following initial diagnosis, the cat was euthanased 28 days later. Squamous cell carcinoma should be considered as a possible differential diagnosis when a cat is presented for investigation of an anal sac mass.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/32935335/