Peer-reviewed veterinary case report
Standard blood clot tests don't show high clot risk in sick dogs
By Clarkin-Breslin, R C et al.·Published in The Journal of small animal practice·2024·Department of Clinical Sciences and Advanced Medicine, United States·View original on PubMed →
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Original publication title: Standard tests of haemostasis do not predict elevated thromboelastographic maximum amplitude, an index of hypercoagulability, in sick dogs.
- Species:
- dog
Plain-English summary
A group of sick dogs was tested to see if standard blood tests could predict a condition called hypercoagulability, which means their blood was too thick and could lead to clots. The tests included measuring prothrombin time, D-dimers, and platelet counts. It turned out that the standard tests did not help in identifying which dogs were hypercoagulable, but higher platelet counts and packed red blood cell volume were linked to this condition. This means that vets may need to rely on more specific tests like thromboelastography to assess blood clotting issues in dogs.
People also search for: dog blood clotting problems · dog hypercoagulability symptoms · dog platelet count treatment
Abstract
OBJECTIVES: To compare standard tests of haemostasis in hypercoagulable and normocoagulable sick dogs as identified by thromboelastography. MATERIALS AND METHODS: We compared prothrombin time, activated partial thromboplastin time, D-dimers, packed red blood cell volume and platelet counts in client-owned sick dogs with hypercoagulable (n = 36) and normocoagulable (n = 35) states as identified by thromboelastography maximum amplitude above or within the established reference interval, respectively. RESULTS: Seventy-one dogs were included. Thirty-six dogs were hypercoagulable and 35 were normocoagulable on thromboelastography. Using multivariable linear models, prothrombin time, activated partial thromboplastin time and D-dimers were not associated with hypercoagulability. Platelet counts and packed red blood cell volume were significantly associated with hypercoagulability. CLINICAL SIGNIFICANCE: Prothrombin time, activated partial thromboplastin time and D-dimers were not useful in the identification of hypercoagulability in dogs as defined by thromboelastography.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/38804082/