Peer-reviewed veterinary case report
Dog had seizures after accidental cefazolin injection during myelogram
By Griffith, Carrie A & Hoffmann, Daniel E·Published in Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)·2013·Akron Veterinary Referral and Emergency Center·View original on PubMed →
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Original publication title: Status epilepticus attributed to inadvertent intrathecal injection of cefazolin during myelography.
- Species:
- dog
Plain-English summary
A 4-year-old male Dachshund suddenly developed weakness in his back legs after a procedure called a myelogram. During the procedure, a medication called cefazolin was accidentally injected into his spine, which caused him to have severe seizures. The veterinary team provided supportive care, and thankfully, the dog made a full recovery. This case serves as a reminder for veterinarians to be careful when giving medications to pets.
People also search for: dog seizures after myelogram · Dachshund hind leg weakness · cefazolin side effects in dogs
Abstract
OBJECTIVE: To describe a case of status epilepticus believed to be a consequence of inadvertent intrathecal administration of cefazolin in a dog undergoing a myelogram. CASE SUMMARY: A 4-year-old, 6.5 kg, male neutered Dachshund was referred for evaluation of an acute onset hind limb paraparesis. While performing a lumbar myelogram, cefazolin was inadvertently injected into the ventral subarachnoid space. Subsequent refractory seizure activity was attributed to the epileptogenic effects of intrathecally administered cefazolin. Supportive therapy led to eventual complete recovery. NEW OR UNIQUE INFORMATION PROVIDED: Although epileptogenic effects of intrathecally administered cefazolin are well documented in the human and experimental animal model literature, to the authors' knowledge this has not been characterized in the veterinary literature. This case highlights the need to be diligent and mindful when one administers medications, and describes the management of a dog adversely affected as a consequence of a medical error.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/24304840/