Peer-reviewed veterinary case report
Stem Cell Therapy.
- Journal:
- The Veterinary clinics of North America. Small animal practice
- Year:
- 2019
- Authors:
- Quimby, Jessica M
- Affiliation:
- Department of Veterinary Clinical Sciences · United States
Plain-English summary
Stem cell therapy is being explored as a promising treatment for different diseases in pets, especially those affecting the kidneys. Researchers are looking into how mesenchymal stem cells, which have special properties that can help regulate the immune system, might be used to treat kidney problems. This review discusses what we currently know about how these stem cells work and summarizes studies on their use in cases of chronic kidney disease and acute kidney injury. The goal is to give a clear picture of where this treatment stands now and what it might offer in the future. Overall, while the potential is exciting, more research is needed to fully understand its effectiveness.
Abstract
Stem cell therapy has tremendous potential for clinical application in the treatment of a variety of diseases in veterinary medicine. Based on the known desirable immunomodulatory properties of mesenchymal stem cells, this therapy has potential for treatment of a variety of renal diseases. This review details our current understanding of stem cell biology and proposed mechanism of action as applicable to renal disease. Studies performed in chronic kidney disease clinical trials and models of acute kidney injury are summarized with the goal of providing an overview of the current status of this treatment modality and its potential for the future.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/30591191/