Peer-reviewed veterinary case report
Outcome of fracture surgery after radiosurgery in 6 dogs with bone
By Covey, Jennifer L et al.·Published in Veterinary surgery : VS·2014·College of Veterinary Medicine, United States·View original on PubMed →
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Original publication title: Stereotactic radiosurgery and fracture fixation in 6 dogs with appendicular osteosarcoma.
- Species:
- dog
Plain-English summary
A group of six dogs with bone cancer (appendicular osteosarcoma) were treated with a special type of radiation therapy (stereotactic radiosurgery) and then had surgery to fix broken bones caused by the cancer. Some dogs had fractures before the radiation, while others developed them afterward. After surgery, most dogs had good limb function as long as there were no infections and the implants held up well. The dogs lived between about one to two and a half years after treatment, showing that this approach can help manage fractures in dogs with this type of cancer.
People also search for: dog bone cancer treatment · appendicular osteosarcoma surgery · dog fracture repair after cancer · stereotactic radiosurgery for dogs
Abstract
OBJECTIVE: To evaluate clinical outcome of dogs with appendicular osteosarcoma (OSA) treated with stereotactic radiosurgery (SRS) and subsequent internal fixation of a pathologic fracture. STUDY DESIGN: Retrospective case series. ANIMALS: Dogs with spontaneous-occurring appendicular OSA (n = 6). METHODS: Medical records (May 2002-January 2008) of dogs that had SRS for appendicular OSA were reviewed. Dogs were included if they had a pathologic fracture either before or after SRS and were treated with internal fixation. Signalment, history, physical examination findings, clinicopathologic data, diagnostic imaging findings, biopsy results, surgical complications, number of surgeries, adjuvant therapy, development of metastatic disease and cause of death were recorded. RESULTS: Six dogs met the inclusion criteria. Two dogs had a pathologic fracture at admission and 4 dogs developed a fracture after SRS with a mean ± SD time to fracture development of 6.25 ± 1.65 months. The first 3 fractures were repaired using an open approach and the latter three using minimally invasive percutaneous osteosynthesis (MIPO). Infection occurred in 5 dogs and implant failure in 3. Limb function was subjectively assessed as good in all dogs when the implants were stable and infections were subclinical. Survival times ranged from 364-897 days; 1 dog was lost to follow-up. CONCLUSIONS: Fracture repair using internal fixation should be considered a viable limb-sparing alternative for pathologic fractures that have been treated with SRS.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/24393054/