Peer-reviewed veterinary case report
Radiation treatment and recovery in dogs with brain meningiomas
By Dolera, Mario et al.·Published in Journal of the American Animal Hospital Association·2018·From the La Cittadina Fondazione Studi e Ricerche Veterinarie, Italy·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Stereotactic Volume Modulated Arc Radiotherapy in Canine Meningiomas: Imaging-Based and Clinical Neurological Posttreatment Evaluation.
- Species:
- dog
Plain-English summary
A group of 39 dogs with brain or spinal tumors called meningiomas were treated with a specialized form of radiation therapy to see how well it worked. The dogs received a total of five high-dose treatments, and their health was closely monitored for changes in behavior, movement, and any seizures. After two years, about 65% of the dogs showed improvement in their condition, with many experiencing a reduction in tumor size. The treatment was generally safe, with very few side effects reported, and most dogs had a good chance of surviving for two years after treatment.
People also search for: dog meningioma treatment · canine brain tumor radiation therapy · dog seizures after radiation
Abstract
A prospective study to assess high-dose hypofractionated volume modulated arc radiotherapy feasibility and efficacy in canine meningiomas was conducted. Thirty-nine patients with encephalic and spinal meningiomas assumed from MRI findings were recruited and received high-dose hypofractionated volumetric modulated arc radiotherapy by a linear accelerator equipped with an external beam modulator micro-multileaf collimator and an XVI cone beam computed tomography system. The prescribed mean dose was 33 Gy in five fractions. The treatment feasibility was tested through planned and delivered dose agreement checks. Regular clinical examinations were performed during and after irradiation time, with regard to mentation, deambulation, cranial nerve dysfunction, and seizures. Serial MRI exams were done 60 days after irradiation and after 4, 6, 12, 18, and 24 mo. Volumetric disease reduction criteria implemented with clinical neurological systematic evaluation were adopted to assess the course and to categorize patients' responses. Complete and partial responses were observed on the whole in 65.5% of alive patients 24 mo after irradiation. Two-yr overall and disease-specific survival rates were 74.3% and 97.4%, respectively, and the putative radiotoxic effects were found to be few and slight.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/29372870/