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Peer-reviewed veterinary case report

Subungual Pigmented Squamous Cell Carcinoma in a Dog.

Journal:
Journal of comparative pathology
Year:
2022
Authors:
Yang, Yeseul et al.
Affiliation:
College of Veterinary Medicine · South Korea
Species:
dog

Abstract

An 11-year-old spayed female Miniature Schnauzer dog was presented with loss of a claw caused by a nail bed mass. Histopathological evaluation revealed that the mass comprised neoplastic squamous cells with abundant cytoplasmic melanin pigment. Immunohistochemically, the neoplastic cells were positive for cytokeratin and negative for vimentin and ionized calcium-binding adaptor molecule 1, supporting a diagnosis of pigmented squamous cell carcinoma. To our knowledge, this is the first report of subungual pigmented squamous cell carcinoma in animals.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/35577459/