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Peer-reviewed veterinary case report

Loss of claw from pigmented nail cancer in Miniature Schnauzer dog

By Yang, Yeseul et al.·Published in Journal of comparative pathology·2022·College of Veterinary Medicine, South Korea·View original on PubMed

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Original publication title: Subungual Pigmented Squamous Cell Carcinoma in a Dog.

Species:
dog

Plain-English summary

An 11-year-old spayed female Miniature Schnauzer was brought to the vet because she had lost a claw due to a mass in her nail bed. Tests showed that the mass was a type of skin cancer called pigmented squamous cell carcinoma, which is rare in dogs. This condition involves abnormal cells that produce pigment and can affect the nail area. The dog will need treatment options discussed with the veterinarian to manage her condition effectively.

People also search for: dog nail bed mass · Miniature Schnauzer claw loss · dog skin cancer treatment

Abstract

An 11-year-old spayed female Miniature Schnauzer dog was presented with loss of a claw caused by a nail bed mass. Histopathological evaluation revealed that the mass comprised neoplastic squamous cells with abundant cytoplasmic melanin pigment. Immunohistochemically, the neoplastic cells were positive for cytokeratin and negative for vimentin and ionized calcium-binding adaptor molecule 1, supporting a diagnosis of pigmented squamous cell carcinoma. To our knowledge, this is the first report of subungual pigmented squamous cell carcinoma in animals.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/35577459/