Peer-reviewed veterinary case report
Dog survives doxorubicin overdose and injection injury with treatment
By Kicenuik, Kristin S et al.·Published in The Canadian veterinary journal = La revue veterinaire canadienne·2018·Department of Small Animal Medicine and Surgery, United States·View original on PubMed →
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Original publication title: Successful management of doxorubicin overdose and extravasation in a dog with lymphoma.
- Species:
- dog
Plain-English summary
A dog was hospitalized after receiving too much doxorubicin, a chemotherapy drug, and the medication leaked out of the vein during treatment. The dog received supportive care and a medication called dexrazoxane to help manage the side effects. By Day 9, the dog's overall health improved, and the injury from the medication leak healed by Day 36. This case shows that with the right treatment, dogs can recover from a doxorubicin overdose and the complications that can arise from it.
People also search for: dog doxorubicin overdose treatment · chemotherapy side effects in dogs · dog lymphoma treatment options
Abstract
A dog was hospitalized after accidental overdose and extravasation of doxorubicin. With supportive care and dexrazoxane, systemic toxicity resolved by Day 9 and extravasation injury by Day 36. This case demonstrates that, with treatment, dogs can survive doxorubicin overdose and extravasation. The report also highlights the importance of checking the dose of chemotherapeutic agents and preventing extravasation.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/30510312/