Peer-reviewed veterinary case report
Cat with mediastinal lymphoma and fluid around heart
By Yu SJ et al.·Published in Veterinární Medicína·2022·Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University, Gwangjin-gu, Seoul, Republic of Korea, CZ·View original on DOAJ →
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Original publication title: Successful management of feline CD4+ CD8+ T-cell mediastinal lymphoma with pericardial effusion
- Species:
- cat
Plain-English summary
A 2-year-old male Russian blue cat was brought to the vet because he was having trouble breathing, was lethargic, and had a bluish tint to his gums. X-rays and scans showed a large mass in his chest, along with fluid around his heart and lungs. After diagnosing him with a type of lymphoma, the vet started a specific chemotherapy treatment that quickly reduced the mass and improved his breathing and appetite. Remarkably, three years later, he is still in complete remission and doing well.
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Abstract
A 2-year-old, castrated, male Russian blue cat presented with acute dyspnoea, cyanosis, and lethargy. A thoracic radiography revealed a large cranial mediastinal mass; the computed tomography revealed caudal lobe atelectasis of the right lung with pericardial and pleural effusions. The cytodiagnostic tests revealed high-grade CD4+ CD8+ T-cell mediastinal lymphoma as clinical stage Vb; l-asparaginase-cyclophosphamide-doxorubicin-vincristine-prednisolone (l-CHOP)-based chemotherapy was initiated, following which the mass shrunk rapidly; 1 week after the initiation of chemotherapy, the appetite-related and respiratory symptoms improved dramatically, and the pleural and pericardial effusion resolved. The patient remains in complete remission three years after the initiation of the l-CHOP chemotherapy. Therefore, the accurate diagnosis and instantaneous initiation of chemotherapy may resolve life-threatening pleural and pericardial effusions in cats with high-grade aberrant T-cell mediastinal lymphoma.
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Search related cases →Original publication on DOAJ: https://doi.org/10.17221/70/2021-VETMED