Peer-reviewed veterinary case report
Dog with non-responsive gut disease improves after one fecal
By Koji Sugita et al.·Published in Journal of Veterinary Medical Science·2021·View original on Semantic Scholar →
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Original publication title: Successful outcome after a single endoscopic fecal microbiota transplantation in a Shiba dog with non-responsive enteropathy during the treatment with chlorambucil
- Species:
- dog
Plain-English summary
A 7-year-old Shiba dog was brought to the vet after suffering from lethargy, loss of appetite, vomiting, and frequent watery diarrhea for a month. Tests showed he had weight loss, low protein levels, anemia, and high white blood cell counts, leading to a diagnosis of non-responsive enteropathy (NRE). After the dog didn't improve with medication, he underwent a fecal microbiota transplantation (FMT), which involved transferring healthy gut bacteria into his intestines. This treatment significantly improved his symptoms and overall health, with no side effects or return of the issues.
People also search for: Shiba dog diarrhea treatment · fecal microbiota transplantation for dogs · dog vomiting and diarrhea causes
Abstract
A 7-year 6-month-old, castrated male Shiba dog presented with a 1-month history of lethargy, anorexia, vomiting, and frequent watery diarrhea. Weight loss, hypoalbuminemia, anemia, and leukocytosis were detected at the first visit. The dog was diagnosed with non-responsive enteropathy (NRE) based on clinical and histopathological examinations. Since the dog did not respond to the immunosuppressive drugs, fecal microbiota transplantation (FMT) was performed during the treatment with chlorambucil. A single endoscopic FMT into the cecum and colon drastically recovered clinical signs and clinicopathological abnormalities and corrected dysbiosis in the dog. No recurrence or adverse events were observed. The present case report suggests that FMT, possibly together with chlorambucil, might be a treatment option for NRE in Shiba dogs that have poorer prognosis compared with other dog breeds.
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Search related cases →Original publication on Semantic Scholar: https://www.semanticscholar.org/paper/33896875