Peer-reviewed veterinary case report
Dogs with esophageal spirocercosis cured by daily oral doramectin
By Lobetti, Remo·Published in Veterinary journal (London, England : 1997)·2012·Bryanston Veterinary Hospital·View original on PubMed →
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Original publication title: Successful resolution of oesophageal spirocercosis in 20 dogs following daily treatment with oral doramectin.
- Species:
- dog
Plain-English summary
Twenty dogs with a condition called spirocercosis, which involves nodules in the esophagus, were treated with a daily oral medication called doramectin. After 42 days of treatment, 13 dogs showed complete resolution of the nodules, while five more improved after an additional 42 days. The last two dogs needed a total of 126 days of treatment to fully recover. Throughout the treatment, no side effects were reported, and doramectin proved to be effective in eliminating the nodules.
People also search for: dog esophagus nodules treatment · spirocercosis in dogs · doramectin for dogs spirocercosis
Abstract
The purpose of this study was to evaluate the effect of a daily oral dose of doramectin in dogs with spirocercosis. Twenty naturally infected dogs were treated with 0.5 mg/kg doramectin administered orally once daily for 42 days. In 13 of the dogs there was resolution of the nodules after 42 days. Nodules were eliminated in five of the remaining seven dogs following treatment for an additional 42 days. In the remaining two dogs, treatment continued for a further 42 days (total 126 days), resulting in complete resolution. No adverse events associated with treatment were observed. This study concluded that doramectin at 0.5 mg/kg once a day is effective in the elimination of Spirocerca lupi nodules in dogs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/22000593/