Peer-reviewed veterinary case report
Dog with bifenthrin poisoning treated successfully with plasma
By Fitzgerald, Alyson H et al.·Published in Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)·2024·Department of Clinical Sciences, United States·View original on PubMed →
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Original publication title: Successful treatment of bifenthrin toxicosis using therapeutic plasma exchange.
- Species:
- dog
Plain-English summary
An 8-month-old female poodle mix was brought to the vet after eating a pesticide called bifenthrin, which caused severe shaking, confusion, and nerve issues. Despite initial treatments like fluids and medications, her condition didn't improve, so the vet decided to try a procedure called therapeutic plasma exchange (TPE). Unfortunately, she went into cardiac arrest during the treatment but was successfully revived. After the procedure, her symptoms significantly improved, and the level of bifenthrin in her blood dropped dramatically.
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Abstract
OBJECTIVE: To describe a case of bifenthrin toxicosis in a dog with a successful outcome following the use of therapeutic plasma exchange (TPE) and intralipid therapy. CASE SUMMARY: An 8-month-old female neutered poodle mix dog ingested an unknown amount of powered bifenthrin, which resulted in acutely altered mentation, cranial nerve deficits, and intractable tremors that persisted in severity despite aggressive medical management to include intravenous fluids, intravenous lipid emulsion, anticonvulsant medications, and methocarbamol. TPE was initiated after lack of significant clinical improvement 12 hours after initial presentation. The dog underwent cardiopulmonary arrest (CPA) following approximately 1 plasma volume equivalent exchange. The dog was successfully resuscitated and showed marked improvement 12 hours postarrest and post-TPE treatment. Serum bifenthrin concentrations were analyzed prior to TPE (445.38 ng/mL) and ∼10 hours after TPE (51.18 ng/mL), which resulted in an 89% reduction in serum bifenthrin concentration. NEW INFORMATION: TPE may be a promising adjunctive therapeutic modality for bifenthrin toxicosis in dogs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/38708999/