Peer-reviewed veterinary case report
Successful terbinafine treatment for sporotrichosis in dogs
By Viana, Paula Gonçalves et al.·Published in Mycopathologia·2018·Evandro Chagas National Institute of Infectious Diseases, Brazil·View original on PubMed →
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Original publication title: Successful Treatment of Canine Sporotrichosis with Terbinafine: Case Reports and Literature Review.
- Species:
- dog
Plain-English summary
Two dogs in Brazil were diagnosed with sporotrichosis, a fungal infection that can cause skin and respiratory issues. One dog had skin lesions, while the other showed redness in the nose and breathing problems. Both dogs were treated with an antifungal medication called terbinafine, which proved to be very effective. After treatment, both dogs showed complete recovery and no longer displayed any symptoms of the infection. This suggests that terbinafine could be a good option for treating sporotrichosis in dogs.
People also search for: dog skin infection treatment · dog breathing problems antifungal · sporotrichosis in dogs symptoms
Abstract
Sporotrichosis occurs worldwide, and the metropolitan region of Rio de Janeiro, Brazil, is a main endemic area, with a large number of human and animal cases in the last 19 years. This mycosis is more frequently described in cats rather than in dogs. There are a limited number of oral antifungal agents for the treatment of sporotrichosis in animals. In this context, the effectiveness of terbinafine in the treatment of sporotrichosis in humans, as well as the promising results of in vitro susceptibility tests, inspired us to use this drug in the therapy of this mycosis in dogs. We reported for the first time the use of terbinafine in the treatment of two dogs with sporotrichosis caused by Sporothrix brasiliensis. Moreover, we provided an overview of therapeutic features of canine sporotrichosis cases reported since the 1960s. One of the dogs presented the fixed cutaneous form of the disease, while the other patient presented hyperemia of the nasal mucosa and respiratory signs only. Terbinafine showed high antifungal activity in vitro against the canine Sporothrix isolates. The dogs were successfully treated with terbinafine, with remission of all clinical signs initially presented. The current reports indicate that this drug can emerge as a therapeutic option for canine sporotrichosis.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/29222709/