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Peer-reviewed veterinary case report

Dog with severe skin disease linked to pancreatic tumor and high

By Torres, S et al.·Published in The Journal of small animal practice·1997·Department of Small Animal Clinical Sciences, United States·View original on PubMed

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Original publication title: Superficial necrolytic dermatitis and a pancreatic endocrine tumour in a dog.

Species:
dog

Plain-English summary

A 13-year-old dog was brought in for severe skin problems that had lasted for a year. Tests showed the dog had superficial necrolytic dermatitis, a serious skin condition, along with high blood sugar levels, which suggested a pancreatic endocrine tumor. Despite treatment, the dog's condition did not improve, and unfortunately, the decision was made to euthanize the dog. A postmortem examination confirmed the presence of the pancreatic tumor and that it had spread to the liver.

People also search for: dog skin problems · pancreatic tumor in dogs · superficial necrolytic dermatitis treatment

Abstract

A 13-year-old dog was referred for a severe dermatological problem of 12 months duration. Skin biopsy results were compatible with superficial necrolytic dermatitis. The only laboratory abnormalities were hyperglycaemia and hyperglucagonaemia. These findings suggested a pancreatic endocrine tumour in association with superficial necrolytic dermatitis. Abdominal ultrasound examination was unremarkable. The dog was euthanased due to the lack of clinical improvement following symptomatic therapy. Postmortem examination revealed a pancreatic endocrine tumour with liver metastases. Pancreatic endocrine tumour cells were immunoreactive for glucagon, insulin and islet amyloid polypeptide.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/9200114/