Peer-reviewed veterinary case report
Surgery with or without doxorubicin for injection-site sarcomas
By Martano, Marina et al.·Published in Veterinary journal (London, England : 1997)·2005·Department of Animal Pathology, Italy·View original on PubMed →
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Original publication title: Surgery alone versus surgery and doxorubicin for the treatment of feline injection-site sarcomas: a report on 69 cases.
- Species:
- cat
Plain-English summary
Sixty-nine cats with injection-site sarcomas, which are tumors that can develop at vaccination sites, were treated at a veterinary hospital in Italy. Some cats received surgery along with a chemotherapy drug called doxorubicin, while others only had surgery. After monitoring the cats, it was found that the recurrence of tumors and spread to the lungs happened in similar rates for both treatment groups. In the end, more cats in the chemotherapy group were alive, but the differences in outcomes were not significant.
People also search for: cat injection-site sarcoma treatment · doxorubicin for cats · cat tumor surgery recovery
Abstract
Sixty-nine cats were treated for injection-site sarcomas at the Veterinary Teaching Hospital of Grugliasco, Turin (Italy). The animals were divided into two subgroups: those subjected to four doxorubicin cycles combined with radical surgical excision 10 days after the second chemotherapy cycle (group A, 49 cats) or those treated with surgery alone (group B, 20 cats). Each cat was monitored for lung metastasis and local recurrence. In group A, 28 cats were alive at the end of the follow-up period. In this group, the recurrence rate was 40.8% while lung metastasis occurred in 12% of cats. In group B, eight animals were alive at the end of the follow-up period, while the rates of recurrence and metastasis were 35% and 10%. Neither the median disease-free interval nor the median overall survival was reached in either group. Moreover, there were no statistically significant differences between the two groups.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15993791/