Susceptibility to Bacteriocins of Multiresistant,Gene PossessingStrains from Lesions on Dogs in Vojvodina (Serbia).

Abstract

Staphylococci are considered commensal organisms; however, they can also cause diseases in animals. The specieswas originally isolated from the nares and anal mucosa of healthy dogs; nowadays, the incidence of methicillin-resistantstrains in dogs has increased, and this species has also become the most common cause of canine skin lesions.were tested for their susceptibility to bacteriocins to show the potential of bacteriocins to eliminate/reduceas a causative agent.In this study,were isolated from skin lesions on dogs of various breeds and ages in the Vojvodina region (Serbia) in the framework of our international co-operation.strains were identified using matrix-assisted laser desorption ionization time-of-flight mass spectrometry, and the species allocation was confirmed by genotypization and corroborated using phenotyping tests. The strains were multiresistant, involving methicillin-resistance. In addition, theA gene was detected instrains, confirming the presence of a genetic feature for methicillin resistance.strains produced large amounts of the enzymes alkaline phosphatase and acid phosphatase; they were low-grade biofilm forming (0.1 &#x2264;< 1.0), except.SPs1. All strains were susceptible to gallidermin (inhibition activity up to 204,800 arbitrary unit [AU]/mL); however, they were mostly resistant to enterocins. However, biofilm-formingSPs1 was susceptible to enterocins (200 AU/mL).Establishing the susceptibility of multiresistant andgene-possessingstrains to gallidermin is an innovative, original result; it provides a new opportunity for preventing/eliminating infection caused by those agents.