Peer-reviewed veterinary case report
Dog turned blue after hydrogen peroxide given for ibuprofen poisoning
By Dominguez, Dominique & Walton, Rebecca·Published in The Canadian veterinary journal = La revue veterinaire canadienne·2025·VCA West Los Angeles Animal Hospital, United States·View original on PubMed →
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Original publication title: Suspected clinical methemoglobinemia associated with administration of hydrogen peroxide 3% in a dog treated for acute ibuprofen ingestion.
- Species:
- dog
Plain-English summary
An 8-month-old male golden retriever collapsed and turned blue after receiving hydrogen peroxide to make him vomit due to ibuprofen ingestion. Tests showed he had a serious condition called methemoglobinemia, which means his blood wasn't carrying oxygen properly. Fortunately, after 24 hours of supportive care at the hospital, his condition improved and he recovered. This case highlights the risks of using hydrogen peroxide in dogs, especially after certain types of poisoning.
People also search for: dog collapsed after hydrogen peroxide · golden retriever ibuprofen poisoning · methemoglobinemia treatment in dogs
Abstract
An 8-month-old intact male golden retriever dog was presented to the emergency department of a large private-practice specialty hospital. The dog had become cyanotic and collapsed following administration (orogastric tube) of 1.4 mL/kg of hydrogen peroxide 3% to induce emesis for ibuprofen ingestion. The dog had severe methemoglobinemia (33%; reference range: 0.3 to 1.5%) and developed anemia. The methemoglobinemia resolved after 24 h of hospitalization with supportive care. Results from assessment with high-performance liquid chromatography/tandem mass spectrometry were consistent with ibuprofen ingestion, with no acetaminophen detected. Key clinical message: This case demonstrated methemoglobinemia in a dog following both ibuprofen ingestion and hydrogen peroxide 3% administration.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/40510286/