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Peer-reviewed veterinary case report

Portuguese water dog with immune neutropenia and steroid-responsive

By Denstedt, Ellen B·Published in The Canadian veterinary journal = La revue veterinaire canadienne·2017·Ontario Veterinary College, Canada·View original on PubMed

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Original publication title: Suspected immune-mediated neutropenia and corticosteroid responsive pancytopenia in a Portuguese water dog.

Species:
dog

Plain-English summary

An 8-year-old spayed Portuguese water dog was brought in because she was having trouble urinating, was very tired, and had lost her appetite. Blood tests showed she had very low levels of white blood cells and other blood components, indicating a serious condition. After examining her bone marrow, the vet suspected that her immune system was mistakenly attacking her blood cells. The dog was treated with immunosuppressive medication, and her symptoms improved significantly.

People also search for: dog lethargy and loss of appetite · Portuguese water dog immune system problems · treatment for low white blood cells in dogs

Abstract

An 8-year-old spayed Portuguese water dog was presented with dysuria, lethargy, and anorexia. A profound neutropenia and pancytopenia were identified. Bone marrow aspirates revealed neutrophilic hyperplasia, a significant left shift, and toxic changes, suggesting immune-mediated destruction as a likely underlying mechanism. Immunosuppressive therapy was instituted and clinical signs improved.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/28042161/