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Peer-reviewed veterinary case report

Suspected immune-mediated neutropenia and corticosteroid responsive pancytopenia in a Portuguese water dog.

Journal:
The Canadian veterinary journal = La revue veterinaire canadienne
Year:
2017
Authors:
Denstedt, Ellen B
Affiliation:
Ontario Veterinary College · Canada
Species:
dog

Abstract

An 8-year-old spayed Portuguese water dog was presented with dysuria, lethargy, and anorexia. A profound neutropenia and pancytopenia were identified. Bone marrow aspirates revealed neutrophilic hyperplasia, a significant left shift, and toxic changes, suggesting immune-mediated destruction as a likely underlying mechanism. Immunosuppressive therapy was instituted and clinical signs improved.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/28042161/