Peer-reviewed veterinary case report
Donge de Bordeaux dog with suspected immune deficiency causing gut
By Lobetti, R G·Published in Journal of the South African Veterinary Association·2002·Bryanston Veterinary Hospital·View original on PubMed →
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Original publication title: Suspected primary immune deficiency in a Donge de Bordeaux dog.
- Species:
- dog
Plain-English summary
A young Donge de Bordeaux dog was brought in because it had ongoing stomach and breathing issues that improved with antibiotics but kept coming back. Tests revealed that the dog had bacterial infections in its lymph nodes and trachea, along with low levels of certain immune cells (B-lymphocytes) that help fight infections. The presence of T-lymphocytes indicated that the dog's immune system was not functioning properly, likely due to a genetic condition affecting its ability to produce B-cells. The vet suspected a primary immune deficiency and recommended further monitoring and treatment options to manage the dog's health.
People also search for: dog breathing problems · Donge de Bordeaux immune deficiency · chronic gastrointestinal issues in dogs
Abstract
A young Donge de Bordeaux dog was presented with chronic intermittent antibiotic responsive gastrointestinal and respiratory disease. Further evaluation showed bacterial lymphadenitis, bacterial tracheitis, normal white cell and differential cell counts, hypogammaglobulinaemia, and the absence of B-lymphocytes but the presence of T-lymphocytes in the lymphoid tissue stained with lymphocyte markers. As the dog came from a narrow genetic base, with related dogs showing similar clinical signs, possible B-cell congenital immune deficiency was suspected.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/12515302/