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Peer-reviewed veterinary case report

Cat with hind foot skin death linked to multicentric lymphoma

By Ashley, P F & Bowman, L A·Published in Journal of the American Veterinary Medical Association·1999·Department of Small Animal Clinical Sciences, United States·View original on PubMed

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Original publication title: Symmetric cutaneous necrosis of the hind feet and multicentric follicular lymphoma in a cat.

Species:
cat
LymphomaStomach & digestionCats

Plain-English summary

A 7-year-old male domestic shorthair cat was brought to the vet because the skin on its hind feet was dying and it had high liver enzyme levels. After tests, the cat was diagnosed with multicentric follicular lymphoma, a type of cancer, but the owner chose not to pursue treatment. Sadly, the cat passed away, and further examination revealed the lymphoma had spread to the liver, stomach, and lymph nodes. The skin issues on the feet were linked to the cancer, which can sometimes cause similar symptoms in pets.

People also search for: cat skin problems · cat lymphoma treatment options · why is my cat's foot necrotic · high liver enzymes in cats · symptoms of lymphoma in cats

Abstract

A 7-year-old castrated male domestic shorthair cat was admitted to the veterinary teaching hospital for evaluation of symmetric necrosis of the skin of its hind feet and high liver enzyme activities. Lymphoma was diagnosed on cytologic examination of a fine needle aspirate of the liver. The owner declined treatment for the lymphoma. On postmortem histologic examination, lymphoma was found in the liver, stomach, and multiple lymph nodes. Immunohistochemical staining revealed the neoplasm to have a mixed B- and T-cell follicular arrangement, and a diagnosis of multicentric follicular lymphoma was made. The distal portion of the feet were necrotic, but a neoplastic infiltrate was not seen on histologic examination. After thrombosis and vasculitis were excluded as causes, the ischemic necrosis of the feet of the cat in this report was considered a paraneoplastic syndrome, as can be seen in people with lymphoma or other internal malignancies.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/9926010/