Peer-reviewed veterinary case report
How SDMA blood test helps detect kidney disease early in dogs and cats
By Relford, Roberta et al.·Published in The Veterinary clinics of North America. Small animal practice·2016·Companion Animal Group Medical Organization, United States·View original on PubMed →
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Original publication title: Symmetric Dimethylarginine: Improving the Diagnosis and Staging of Chronic Kidney Disease in Small Animals.
Plain-English summary
Chronic kidney disease (CKD) is a common issue in cats and dogs, often diagnosed only after significant kidney function loss. A new test measuring symmetric dimethylarginine (SDMA) can detect kidney problems earlier than traditional tests that look at creatinine levels. This SDMA test is not influenced by the pet's body size, making it a more reliable option for diagnosing and managing kidney disease. It has been included in guidelines to help veterinarians better stage the disease and provide targeted treatments. Early detection can lead to better outcomes for pets with kidney issues.
People also search for: dog kidney disease symptoms · cat kidney disease test · early signs of kidney disease in pets
Abstract
Chronic kidney disease (CKD) is a common condition in cats and dogs, traditionally diagnosed after substantial loss of kidney function when serum creatinine concentrations increase. Symmetric dimethylarginine (SDMA) is a sensitive circulating kidney biomarker whose concentrations increase earlier than creatinine as glomerular filtration rate decreases. Unlike creatinine SDMA is unaffected by lean body mass. The IDEXX SDMA test introduces a clinically relevant and reliable tool for the diagnosis and management of kidney disease. SDMA has been provisionally incorporated into the International Renal Interest Society guidelines for CKD to aid staging and targeted treatment of early and advanced disease.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/27499007/