Peer-reviewed veterinary case report
Dog with rare blood cell growth in joint causing arthritis signs
By Talsma, Bryce et al.·Published in Journal of the American Veterinary Medical Association·2024·View original on PubMed →
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Original publication title: Synovial extramedullary hematopoiesis in a dog.
- Species:
- dog
Plain-English summary
A dog was brought in with symptoms similar to immune-mediated polyarthritis, which included joint pain and swelling. After testing, the vet discovered that the dog had a rare condition called extramedullary hematopoiesis, where blood cell production occurs in the joints. The dog was also diagnosed with immune-mediated hemolytic anemia and thrombocytopenia, which are conditions affecting red blood cells and platelets. The treatment involved medications like pregabalin, prednisolone, clopidogrel, and cyclosporine, and after several follow-up visits, the dog's symptoms improved significantly and resolved.
People also search for: dog joint pain · immune-mediated hemolytic anemia treatment · dog arthritis medication · dog swelling in joints
Abstract
OBJECTIVE: Synovial extramedullary hematopoiesis is a rarely reported condition in humans and, to date, has never been reported in canines. This case report describes the clinical presentation, diagnostic work-up, treatment, and outcome of a canine case confirmed to have hematopoietic tissue within multiple joints. ANIMAL: A client-owned canine. CLINICAL PRESENTATION, PROGRESSION, AND PROCEDURES: The clinical presentation was most consistent with immune-mediated polyarthritis, and arthrocentesis was performed in multiple joints for cytological evaluation and culture. Cytology revealed evidence of extramedullary hematopoiesis, and shortly thereafter the dog was diagnosed with immune-mediated hemolytic anemia and thrombocytopenia. TREATMENT AND OUTCOME: Pregabalin, prednisolone, clopidogrel, and cyclosporine were started, and after several recheck appointments and dose adjustments, the dog's clinical signs resolved for all conditions. CLINICAL RELEVANCE: Unusual sites of extramedullary hematopoietic tissue may result in a clinical presentation for which more traditional etiologies and differentials are not applicable.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/38266389/