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Peer-reviewed veterinary case report

T-cell chronic lymphocytic leukemia in a double yellow-headed Amazon

By Osofsky, Anna et al.·Published in Journal of avian medicine and surgery·2011·William R Pritchard Veterinary Medical Teaching Hospital, United States·View original on PubMed

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Original publication title: T-cell chronic lymphocytic leukemia in a double yellow-headed Amazon parrot (Amazona ochrocephala oratrix).

Species:
bird
LymphomaStomach & digestionBirds

Plain-English summary

A male double yellow-headed Amazon parrot was diagnosed with chronic lymphocytic leukemia after blood tests and a bone marrow sample showed abnormal cells. The vet tried treating him with an oral medication called chlorambucil, but unfortunately, there was no improvement after 40 days. Sadly, the parrot was euthanized, and further examination confirmed the leukemia had spread to various organs. This case highlights the challenges of treating certain types of cancer in birds.

People also search for: parrot leukemia treatment · double yellow-headed Amazon parrot cancer · signs of illness in parrots

Abstract

An adult, male double yellow-headed Amazon parrot (Amazona ochrocephala oratrix) was diagnosed with chronic lymphocytic leukemia based on results of a complete blood cell count and cytologic examination of a bone marrow aspirate. Treatment with oral chlorambucil was attempted, but no response was evident after 40 days. The bird was euthanatized, and the diagnosis of chronic lymphocytic leukemia was confirmed on gross and microscopic examination of tissues. Neoplastic lymphocytes were found in the bone marrow, liver, kidney, testes, and blood vessels. Based on CD3-positive immunocytochemical and immunohistochemical immunophenotyping, the chronic lymphocytic leukemia was determined to be of T-cell origin.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/22458185/