Peer-reviewed veterinary case report
Heart function and damage markers in dogs with parvoviral enteritis
By Kocaturk, Meric et al.·Published in Research in veterinary science·2012·Department of Internal Medicine·View original on PubMed →
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Original publication title: Tei index (myocardial performance index) and cardiac biomarkers in dogs with parvoviral enteritis.
- Species:
- dog
Plain-English summary
A group of dogs with parvoviral enteritis (a serious viral infection) were evaluated for heart function and damage. Researchers found that dogs who did not survive had higher levels of certain heart markers and a worse heart performance index compared to those who recovered. This suggests that elevated heart markers can indicate a poor prognosis in dogs with this illness. Unfortunately, many dogs with severe symptoms did not make it, while those with better heart function and lower markers had a chance to recover with treatment.
People also search for: dog parvovirus symptoms · heart problems in dogs with parvo · canine parvoviral enteritis treatment
Abstract
Tei index (myocardial performance) and cardiac biomarkers were evaluated in dogs with parvoviral enteritis (PVE). Tei index was calculated as isovolumic contraction time plus isovolumic relaxation time divided by ejection time. Myocardial and skeletal muscle damages were assessed by serum levels of cardiac troponin I (cTnI), creatine (phospho) kinase, lactate dehydrogenase and aspartate aminotransferase. Serum magnesium level was also determined. According to treatment response, dogs were divided into the survivor (n=20) and non-survivor groups (n=23). Seven healthy dogs served as controls. The mean value of the Tei index was higher in non-survivors, compared with survivors (p<0.02) and healthy controls (p<0.01). Serum level of cTnI in non-survivors was higher than that of survivors and controls (p<0.05). Tei index showed the highest sensitivity and specificity to predict mortality. The findings of an elevated Tei index and an increase in serum cTnI are factors associated with a poor prognosis in cases of canine parvovirosis.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21074228/