Peer-reviewed veterinary case report
Seizures in Cavalier King Charles spaniels with Chiari-like
By Driver, C J et al.·Published in Veterinary journal (London, England : 1997)·2013·Department of Veterinary Clinical Sciences, United Kingdom·View original on PubMed →
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Original publication title: The association between Chiari-like malformation, ventriculomegaly and seizures in cavalier King Charles spaniels.
Plain-English summary
A group of Cavalier King Charles Spaniels (CKCS) with Chiari-like malformation (a brain condition) were studied to understand why some had seizures. Out of 85 dogs, 27 experienced seizures, but researchers found no link between brain enlargement or overcrowding and these seizures. Most of the seizures were classified as partial onset, suggesting that another cause, like familial epilepsy, might be responsible for the seizures in these dogs. While the exact reason for the seizures remains unclear, it’s important for owners to discuss any seizure activity with their veterinarian for proper diagnosis and management.
People also search for: Cavalier King Charles Spaniel seizures · Chiari-like malformation in dogs · CKCS epilepsy treatment
Abstract
Cavalier King Charles spaniels (CKCSs) with Chiari-like malformation (CM) and associated seizures are frequently diagnosed with idiopathic epilepsy. There could be an association between ventriculomegaly (V) or caudal fossa overcrowding (CCFP) and seizures. A retrospective case-control study was performed using MRI to investigate the possible association between these morphological abnormalities and seizures. Seizure semiology and, where possible, electroencephalographic (EEG) abnormalities were documented. Eighty-five CKCS with CM were included, 27 with seizures. There was no association between V or CCFP and seizures (P=0.10 and 0.71, respectively). Seizures were classified as having partial onset in 61% of individuals in the study population (95% CI 42.41-76.43%). Another cause of recurrent seizures in CKCS (such as familial epilepsy) is suspected, as previously reported.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/22749114/