Peer-reviewed veterinary case report
Using dynamic contrast MRI to diagnose dog soft tissue tumors
By Cho, Chang-Hyeon et al.·Published in Veterinary Sciences·2024·Department of Veterinary Medical Imaging, College of Veterinary Medicine, Konkuk University, Seoul 05029, Republic of Korea, South Korea·View original on Crossref →
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Original publication title: The Clinical Application of Dynamic Contrast-Enhanced MRI in Canine Masses of Mesenchymal and Epithelial Origin: A Preliminary Case Series
- Species:
- dog
Plain-English summary
A 7-year-old mixed-breed dog was diagnosed with a soft tissue mass, which raised concerns about whether it was benign or malignant. The dog underwent several imaging tests, including CT and MRI, to assess the mass. The study found that a specific measurement called Ktrans, which indicates blood flow and tissue characteristics, could help determine if the mass is more likely to be cancerous. This means that using Ktrans in imaging could improve how veterinarians evaluate masses in dogs, potentially leading to better treatment decisions.
People also search for: dog soft tissue mass diagnosis · Ktrans in dog tumors · canine cancer imaging techniques
Abstract
Evaluating masses of mesenchymal and epithelial origin accurately using computed tomography (CT) has several limitations in dogs. This study aimed to present dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) parameters to aid in improving the diagnostic accuracy for masses of mesenchymal and epithelial origin in veterinary medicine. Four dogs diagnosed with benign and malignant soft tissue sarcoma (STS), cholesteatoma, or squamous cell carcinoma underwent CT, conventional MRI, and DCE-MRI. Ktrans is a quantitative DCE-MRI parameter representing vascular permeability and tissue perfusion and is related to the potential for malignancy. Hemangiopericytomas (Grade II, STS) showed a higher Ktrans than normal muscle tissue and myxosarcoma (Grade I, STS). Squamous cell carcinoma (a malignant epithelial tumor) also showed a higher Ktrans than normal muscle tissue and cholesteatoma (a mass originating from keratinized squamous epithelium). These results suggest that higher Ktrans values may indicate a greater likelihood that a lesion is more malignant. In conclusion, Ktrans might be useful as a biomarker for evaluating the malignancy of a mass and as an indicator of lesion characteristics in dogs.
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Search related cases →Original publication on Crossref: https://doi.org/10.3390/vetsci11110539