Peer-reviewed veterinary case report
Dog with leishmaniosis and nosebleeds treated successfully
By Best, Matthew P et al.·Published in Veterinary parasitology·2014·Brisbane Veterinary Specialist Centre, Australia·View original on PubMed →
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Original publication title: The diagnosis and management of a case of leishmaniosis in a dog imported to Australia.
- Species:
- dog
Plain-English summary
A dog imported from Europe developed nosebleeds and low red blood cell counts five years later, leading to a diagnosis of leishmaniosis, a disease caused by a parasite. Tests confirmed the presence of the Leishmania infantum parasite in the dog's body. The dog was treated with amphotericin B, a medication that showed a strong positive response. This case highlights the importance of thorough testing for diseases that are not common in certain areas, like Australia.
People also search for: dog nosebleeds treatment · leishmaniosis in dogs · amphotericin B for dogs · dog low red blood cell count causes
Abstract
This case study discusses in detail for the first time the diagnosis and management of a case of leishmaniosis in a dog imported to Australia. The dog presented with epistaxis and a non-regenerative anaemia five years after being imported from Europe. Protozoa were identified within macrophages in bone marrow and splenic cytology. A Leishmania indirect fluorescent antibody test was performed and was positive while an Ehrlichia canis antibody test was negative. Polymerase chain reaction of the ITS-1 and ITS-2 regions of skin, lymph node, spleen and bone marrow were all positive for Leishmania infantum. The dog was treated with amphotericin B with a strong clinical response. The importance of thorough diagnostics in non-endemic areas, particularly Australia, is discussed. Treatment with amphotericin B is discussed. Vigilance, disease reporting and response frameworks are recommended for non-endemic areas.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/24768315/