Peer-reviewed veterinary case report
The effects of ginsenoside Re and its metabolite, ginsenoside Rh1, on 12-O-tetradecanoylphorbol 13-acetate- and oxazolone-induced mouse dermatitis models.
- Journal:
- Planta medica
- Year:
- 2006
- Authors:
- Shin, Yong-Wook et al.
- Affiliation:
- College of Pharmacy · South Korea
Abstract
The effects of the main constituent ginsenoside Re in ginseng and its metabolite, ginsenoside Rh1, were investigated in 12-O-tetradecanoylphorbol 13-acetate (TPA)- and oxazolone-induced mouse ear dermatitis models. Ginsenoside Rh1 potently suppressed the TPA- and oxazolone-induced swellings as well as mRNA expression levels of cyclooxygenase-2, IL-1beta and TNF-alpha, although these were only weakly inhibited by ginsenoside Re.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/16557482/