Peer-reviewed veterinary case report
The increase in tumor oxygenation under carbogen breathing induces a decrease in the uptake of [(18)F]-fluoro-deoxy-glucose.
- Journal:
- Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
- Year:
- 2015
- Authors:
- Neveu, Marie-Aline et al.
- Affiliation:
- Biomedical Magnetic Resonance Research Group
Abstract
We investigated the impact of oxygenation status (measured by EPR oximetry) on the uptake of (18)F-FDG (measured by PET) in two different tumor models during a carbogen breathing challenge. We observed a significant drop in (18)F-FDG uptake under carbogen breathing that suggests a rapid metabolic adaptation to the oxygen environment.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/25981053/