Peer-reviewed veterinary case report
Staging and treatment options for high-grade lymphoma in dogs
By Marconato, Laura·Published in Veterinary journal (London, England : 1997)·2011·Animal Oncology and Imaging Center·View original on PubMed →
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Original publication title: The staging and treatment of multicentric high-grade lymphoma in dogs: a review of recent developments and future prospects.
- Species:
- dog
Plain-English summary
Recent research has improved our understanding of high-grade multicentric lymphoma in dogs, which is a serious type of cancer that affects multiple lymph nodes. This has led to better ways to classify the disease and the development of more personalized treatment options. While using a combination of chemotherapy can sometimes lead to complete remission, many dogs still face a high risk of dying from this cancer. The review discusses various treatment methods, including chemotherapy, bone marrow transplants, radiation therapy, and new targeted therapies, as well as how to manage cases that come back or don’t respond to treatment. Overall, while there are promising treatments, the challenge of high mortality rates remains significant.
Abstract
In recent years, considerable progress has been made in understanding the biology of canine lymphoma with resultant enhanced classification schemes and the possibility of individualised, tailored therapies. However, although complete remission may be achieved using multi-agent chemotherapy, the mortality rate from this neoplasm remains high. This review focuses on the staging of high-grade multicentric lymphoma in the dog, on conventional and novel treatment strategies (including chemotherapy, bone marrow transplantation, radiation therapy and molecular-targeted agents), and on the management of relapsed or refractory cases.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/20627636/