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Peer-reviewed veterinary case report

How vaccines and treatments help dogs with parvovirus

By Liu, Luoning·Published in Theoretical and Natural Science·2023·RDFZxishan school·View original on Crossref

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Original publication title: The treatment of Canine Parvovirus and the vaccine improve

Species:
dog

Plain-English summary

A study found that Canine Parvovirus (CPV) is a serious threat to dogs, with a high risk of death if infected. The best way to protect your dog is through vaccination, specifically with the pentavalent vaccine, which significantly lowers the mortality rate. While there are various vaccines available, researchers are exploring a new DNA vaccine that could offer even better protection. Vaccination is crucial since there is no effective treatment for dogs that contract CPV. Keeping your dog up to date on vaccinations is essential for their health and safety.

People also search for: dog parvovirus symptoms · canine parvovirus vaccine effectiveness · how to prevent dog parvovirus

Abstract

Canine Parvovirus (CPV) is common in dogs, with 50% of dogs infected with CPV and 80% of affected dogs likely to die. The main cause of death was myocarditis or enteritis caused by canine parvovirus. However, there is currently no good treatment for CPV infection, only vaccination can prevent it in advance. When dogs receive the inactivated vaccine, the mortality rate can be reduced to 1.25%. At present, there are several methods to treat canine parvovirus, such as inactivated vaccine, attenuated vaccine, gene vaccine and so on. The popular prevent of CPV is to inoculated pentavaccine, a kind of inactivated vaccine. But it needs to inoculated twice. So now, scientist focus on to invent genetic engineering vaccine, that use CPV-2, the DNA of CPV to invent a kind of DNA vaccine, its simple operation and efficient expression of antigen proteins, and some vectors can also be used as biological adjuvants to enhance the immune effect, which are unmatched by traditional vaccines. Inoculated Penta vaccine is the most popular way to prevent CPV but DNA vaccine will become the best way to prevent CPV virus. This paper introduces the vaccine can be used available for Canine parvovirus.

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Original publication on Crossref: https://doi.org/10.54254/2753-8818/8/20240375