The treatment of Canine Parvovirus and the vaccine improve

Abstract

Canine Parvovirus (CPV) is common in dogs, with 50% of dogs infected with CPV and 80% of affected dogs likely to die. The main cause of death was myocarditis or enteritis caused by canine parvovirus. However, there is currently no good treatment for CPV infection, only vaccination can prevent it in advance. When dogs receive the inactivated vaccine, the mortality rate can be reduced to 1.25%. At present, there are several methods to treat canine parvovirus, such as inactivated vaccine, attenuated vaccine, gene vaccine and so on. The popular prevent of CPV is to inoculated pentavaccine, a kind of inactivated vaccine. But it needs to inoculated twice. So now, scientist focus on to invent genetic engineering vaccine, that use CPV-2, the DNA of CPV to invent a kind of DNA vaccine, its simple operation and efficient expression of antigen proteins, and some vectors can also be used as biological adjuvants to enhance the immune effect, which are unmatched by traditional vaccines. Inoculated Penta vaccine is the most popular way to prevent CPV but DNA vaccine will become the best way to prevent CPV virus. This paper introduces the vaccine can be used available for Canine parvovirus.