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Peer-reviewed veterinary case report

The use of caffeine as a respiratory stimulant in a cat.

Journal:
Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)
Year:
2022
Authors:
Kennedy, Christopher R et al.
Affiliation:
Foster Hospital for Small Animals · United States
Species:
cat

Abstract

OBJECTIVE: To report the use of caffeine as a respiratory stimulant in a cat with hypoventilation. CASE SUMMARY: A cat was mechanically ventilated due to persistent hypercapnia (Pco&#xa0;>&#xa0;75&#xa0;mm&#xa0;Hg) following median sternotomy and thymectomy. After 3 days of mechanical ventilatory support, the cat would initiate breaths but failed weaning due to persistent hypercapnia. Following administration of intravenous caffeine (total 12&#xa0;mg/kg over 24&#xa0;h), respiratory and mental status rapidly improved. The cat was subsequently extubated and able to maintain Pvco&#xa0;<&#xa0;50&#xa0;mm&#xa0;Hg. The cat was later diagnosed with myasthenia gravis. Quality of life 13 months after discharge was reported as excellent by her owner. NEW OR UNIQUE INFORMATION PROVIDED: Caffeine may be considered as a respiratory stimulant in cats with hypoventilation.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/35212127/