Peer-reviewed veterinary case report
Dog with rare brain fungal infection treated with liposomal
By Leisewitz, A L et al.·Published in Journal of the South African Veterinary Association·2002·Department of Companion Animal Clinical Studies, United Kingdom·View original on PubMed →
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Original publication title: The use of liposomal amphotericin B in the management of Xylohypha bantiana mycosis in a dog.
- Species:
- dog
Plain-English summary
A 5-year-old mixed-breed dog was diagnosed with a rare fungal infection called Xylohypha bantiana, which typically affects the brain and has not been successfully treated in dogs before. The dog was given a special form of the antifungal medication amphotericin B, known as liposomal amphotericin B, which is safer for use. This treatment helped improve the dog's quality of life and extended its time with its owner, despite the serious nature of the infection.
People also search for: dog brain infection treatment · Xylohypha bantiana in dogs · antifungal medication for dogs
Abstract
Xylohypha bantiana is a rare neurotropic fungal infection reported in humans, dogs and cats. In dogs it has only been identified on post mortem examination and thus no successful treatments have previously been reported. Amphotericin B is a potent antifungal drug with a low therapeutic index because of its nephrotoxicity. Liposomal encapsulation of the drug has resulted in much safer use in humans. This article reports a case of Xylohypha bantiana infection in a dog that was diagnosed antemortally and managed with liposomal amphotericin B, which resulted in the prolongation of quality of life for an infection that invariably results in rapid death.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/12240776/