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Peer-reviewed veterinary case report

Treatment options for immune-mediated hemolytic anemia in dogs

By Goggs, Robert·Published in The Veterinary clinics of North America. Small animal practice·2020·Department of Clinical Sciences, United States·View original on PubMed

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Original publication title: Therapeutic Strategies for Treatment of Immune-Mediated Hemolytic Anemia.

Species:
dog

Plain-English summary

A dog with immune-mediated hemolytic anemia, a condition where the immune system attacks its own red blood cells, was treated with medications to suppress the immune response. The veterinarian used glucocorticoids and may have added other drugs like azathioprine or cyclosporine to help manage the disease. To prevent complications, anticoagulant therapy was started right away, and the dog received a blood transfusion to improve oxygen levels in the blood. With these treatments, the dog was better supported and had a better chance of recovery.

People also search for: dog immune-mediated hemolytic anemia treatment · glucocorticoids for dogs · dog blood transfusion recovery

Abstract

Immune-mediated hemolytic anemia is a common hematologic disorder in dogs. Disease management involves immunosuppression using glucocorticoids, potentially in combination with other medications such as azathioprine, cyclosporine, or mycophenolate mofetil. Therapeutic drug monitoring may enhance the utility and maximize the safety of cyclosporine and mycophenolate mofetil. The disease is proinflammatory and prothrombotic. Antithrombotic drug administration is therefore essential, and anticoagulant therapy should be initiated at the time of diagnosis. Additional therapies include red blood cell transfusion to support blood oxygen content. Future therapies may include therapeutic plasma exchange, anti-CD20 monoclonal antibodies, and complement inhibitors.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/32814628/