Peer-reviewed veterinary case report
Thiamine deficiency and brain signs in dogs from sulphite meat feeding
By Singh, M et al.·Published in Australian veterinary journal·2005·Veterinary Specialist Center, United Kingdom·View original on PubMed →
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Original publication title: Thiamine deficiency in dogs due to the feeding of sulphite preserved meat.
- Species:
- dog
Plain-English summary
A 6-year-old dog was brought in for not eating, losing weight, and vomiting, which quickly led to serious neurological symptoms like seizures and trouble moving. Tests showed a thiamine (vitamin B1) deficiency caused by eating meat preserved with sulphites. After receiving thiamine supplements, the dog improved significantly. A 4-year-old dog and three 7-week-old puppies also showed similar symptoms, with the older dog recovering well after treatment. Unfortunately, one puppy had severe brain damage and did not survive.
People also search for: dog vomiting and seizures · thiamine deficiency in dogs · treatment for dog not eating · puppy neurological symptoms · dog weight loss and vomiting
Abstract
A 6-year-old dog, a 4-year-old dog and three 7-week-old puppies were diagnosed with thiamine deficiency caused by feeding sulphite treated meat. The 6-year-old dog presented with a history of inappetence, weight loss and vomiting that rapidly progressed to signs of multifocal intracranial disease including mental dullness, paresis, seizures, spontaneous nystagmus and strabismus. Thiamine pyrophosphate effect was elevated at 58% and magnetic resonance imaging revealed bilaterally symmetrical hyperintensity of the caudate nucleus and rostral colliculi. The dog recovered with thiamine supplementation. The 4-year-old dog and three 7-week-old puppies also presented with rapidly progressive multifocal central nervous system signs including ataxia, paresis, increased muscle tone, seizures, nystagmus and exophthalmos. The 4-year-old dog made a rapid recovery with thiamine supplementation. Euthanasia and necropsy of a puppy revealed malacia of multiple brainstem nuclei and oedema of the cerebral cortex. These findings were consistent with thiamine deficiency.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16035180/