Peer-reviewed veterinary case report
Third eyelid gland neoplasms of dogs and cats: a retrospective histopathologic study of 145 cases.
- Journal:
- Veterinary ophthalmology
- Year:
- 2016
- Authors:
- Dees, D Dustin et al.
- Affiliation:
- From Eye Care for Animals · United States
Plain-English summary
This study looked at tumors in the third eyelid gland of dogs and cats, focusing on 145 cases. The most common type of tumor found in dogs was adenocarcinoma, which is a cancer that starts in glandular tissue, making up 85% of the cases. In cats, adenocarcinoma was also the most frequent, accounting for 83.3% of the cases. The research showed that while some dogs had a low chance of the cancer spreading or coming back after treatment, cats had a higher risk of both. Overall, the findings suggest that adenocarcinoma is the most common tumor in the third eyelid gland for both species, but cats tend to have worse outcomes compared to dogs.
Abstract
PURPOSE: To describe the various types of primary neoplasms affecting the third eyelid (TEL) gland of dogs and cats. METHODS: A retrospective search of the Comparative Ocular Pathology Laboratory of Wisconsin (COPLOW) database was performed. Veterinary ophthalmologists, primary care veterinarians, and, when appropriate, owners were contacted for patient follow-up information. Patient data points collected included species, age, sex, breed, laterality, tumor type, surgical margins, recurrence, metastasis, and length of follow-up. RESULTS: A total of 127 canine and 18 feline cases met the inclusion criteria. The most common canine TEL gland tumor was adenocarcinoma (n = 108; 85.0%) followed by adenoma (n = 18; 14.2%) and squamous cell carcinoma (SCC) (n = 1; 0.8%). For canine cases with follow-up information available (n = 62), 8.1% had confirmed or suspected metastasis and 11.3% had confirmed or suspected local recurrence of disease. The most common feline TEL gland tumor was adenocarcinoma (n = 15; 83.3%) followed by SCC (n = 3; 16.7%). For feline cases with follow-up information available (n = 9), 40.0% had confirmed or suspected metastasis and 30.0% had confirmed or suspected local recurrence of disease. CONCLUSIONS: This study determined that adenocarcinoma was the most common third eyelid gland tumor in both dogs and cats. The overall survival times were less, and metastatic occurrence and recurrence rates appeared to be higher for feline tumors as compared to those diagnosed in dogs. This is the first report of SCC originating from glandular ductular epithelium.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/25827973/