Peer-reviewed veterinary case report
Third eyelid lymphoma linked to EHV-5 in a mare
By A. Miglio et al.·Published in Journal of Equine Veterinary Science·2018·View original on Semantic Scholar →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Third Eyelid T‐cell‐Rich Large B‐cell Lymphoma Positive to EHV‐5 in a Mare—a Case Report
- Species:
- horse
Plain-English summary
A mare was diagnosed with a rare type of cancer called T-cell-rich large B-cell lymphoma affecting her third eyelid. This condition is unusual in horses, and it was found to be associated with equine herpesvirus-5. The mare underwent surgery to remove the affected tissue, and two years later, there has been no sign of the cancer returning. This case is significant as it highlights a new understanding of lymphoma in horses and its possible connection to a viral infection.
Abstract
Abstract Lymphoma is a rare neoplasm in the horse; nevertheless, it is the most frequent hematopoietic neoplasia in this species. It is classified according to the anatomical distribution of the lesion in multicenter, alimentary, mediastinal, cutaneous, and atypical/solitary form. Extraocular lymphoma mainly occurs as secondary lesion in cutaneous or multicentric form, whereas few reports show the presence of primary form of extraocular lymphoma. Ocular adnexa which are reported to be affected by lymphoma include third eyelid, eyelid, and the cornea. To date, no etiological agents are known. In this case report, we describe a case of T‐cell‐rich large B‐cell lymphoma of the third eyelid in a mare never reported in literature, investigated with histology, immunohistochemistry, and flow cytometry. Moreover, for the first time, the presence of equine herpesvirus‐5 was identified with a biomolecular analysis on the third eyelid tissue affected by lymphoma. HighlightsPrimary extraocular lymphoma is rarely described in the horse.This is the first case of T‐cell‐rich large B‐cell lymphoma of the third eyelid.For the first time, equine herpesvirus‐5 DNA was identified on the extraocular neoplastic tissue.Two years after surgery with no recurrence of neoplasm.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on Semantic Scholar: https://www.semanticscholar.org/paper/31f8789fa58502d0734edc697d1ad332e8c49a46